Use of TpCO2 (Transcutaneous CO2 Measurement) as PaCO2 Predictor During NIV in Case of Acute Hypercapnic Respiratory Failure

University of Lausanne Hospitals20 enrolled

Overview

In patients suffering from hypercapnic respiratory failure and treated by non invasive ventilation (NIV), the interest of using transcutaneous CO2 measurement to evaluate PaCO2 and PaCO2 variation over time is unknown and will be evaluated in this study. Measurements will be done during one-hour NIV treatments.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hypercapnic Respiratory Failure

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ICU patient equipped with an arterial line * NIV treatment prescribed by the clinician in charge * Hypercapnia defined by PaCO2\> 42mmHg Exclusion Criteria: * Severe hemodynamic instability * Severe psychiatric disorders * Denied consent * Age \< 18 years

Locations (1)

Intensive care and burn unit, University hospital of Lausanne

Lausanne, Switzerland

Outcomes

Primary Outcomes

Comparison between TpCO2 (transcutaneous non invasive CO2 partial pressure measurement) and PaCO2 (obtained by blood gas analysis) values during NIV treatment.

Time frame: sixty minutes

Data from ClinicalTrials.gov

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