Zimmer POLAR - Total Knee Arthroplasty (TKA)

Inclusion Criteria: * Patient 18-75 years of age, inclusive; * Patient qualifies for primary total knee arthroplasty based on physical exam and medical history, including diagnosis of severe knee pain and disability due to at least one of the following: * rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis; * collagen disorders and/or avascular necrosis of the femoral condyle; * post-traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy; * moderate valgus, varus, or flexion deformities; * the salvage of previously failed surgical attempts that did not include partial or total knee arthroplasty of the ipsilateral knee; * Patient has participated in a study-related Informed Consent process; * Patient is willing and able to complete scheduled study procedures and follow-up evaluations; * Independent of study participation, patient is a candidate for commercially available Persona fixed bearing knee components implanted in accordance with product labeling. Exclusion Criteria: * Patient is currently participating in any other surgical intervention studies or pain management studies; * Previous history of infection in the affected joint and/or other local/systemic infection that may affect the prosthetic joint; * Insufficient bone stock on femoral or tibial surfaces; * Skeletal immaturity; * Neuropathic arthropathy; * Osteoporosis or any loss of musculature or neuromuscular disease that compromises the affected limb; * Stable, painless arthrodesis in a satisfactory functional position; * Severe instability secondary to the absence of collateral ligament integrity; * Rheumatoid arthritis accompanied by an ulcer of the skin or a history of recurrent breakdown of the skin; * Patient has a known or suspected sensitivity or allergy to one or more of the implant materials; * Patient is pregnant or considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.); * Patient has previously received partial or total knee arthroplasty for the ipsilateral knee.