Evaluating the effect of early application of Continuous positive airway pressure (CPAP) via Neopuff in cases of transient tachypnea of the newborn(TTN) and its role in decreasing the duration and complication of TTN.
The aim of the study is to determine whether positive end expiratory pressure therapy (PEEP) administered early via a T piece based infant resuscitator (Neopuff) would safely reduce the incidence of TTN and the need for neonatal intensive care unit (NICU) admission of near term and term infants with respiratory distress.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
64
* Group I neonates (Experimental group) includes 30 newborns showing signs of TTN who will receive administration of CPAP (5 cm of H2O) via T- piece (Neopuff; Fisher and Paykel Healthcare, Auckland, New Zealand). * Group II neonates (Control group) includes 30 newborns who will receive nasal prong oxygen treatment; standard care according to Siva Subramanian et al. (2010).
Need for admissions to NICU secondary to TTN
Time frame: 24 hours
Levels of plasma brain natriuretic peptide and clinical outcome [Time Frame: 24 hours].
Time frame: 24 hours
Duration of tachypnea.
Time frame: until discharge
Duration and type of oxygen therapy.
Time frame: ntil discharge
Antibiotic treatment.
Time frame: until discharge
Incidence of pulmonary air leaks
Time frame: ntil discharge
Length of hospital (NICU) stay
Time frame: until discharge
Death
Time frame: until discharge
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