Vapocoolant Spray Effectiveness On Arterial Puncture Pain: Randomized Double Blind Placebo-Controlled Trial

Tehran University of Medical Sciences80 enrolled

Overview

This study was aimed to compare pain levels from arterial blood gas (ABG) sampling performed with vapocoolant spray in comparison to placebo.

Previous studies of vapocoolant sprays for reducing pain were mainly on venopuncture with inconsistent results. There was only one prospective open labeled controlled study on arterial blood gas sampling with ethyl chloride which did not show effectiveness. This study will assess the efficacy and tolerability of a topical alkane vapocoolant spray for arterial puncture in adults in comparison to control spray.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Puncture Site Pain

Interventions

Vapocoolant sprayDRUG

The Vapocoolant spray containing alkane is applied for 20 seconds.

Water sprayDRUG

This spray is covered so the patient and the investigator can not find the spray type out.

Eligibility

Sex: ALLMin age: 14 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age of 14 years or older, * needs ABG as a part of their diagnosis Exclusion Criteria: * history of analgesic medication used within 24 hours of enrollment, * any sign of decreased consciousness, * history of skin hypersensitivity, * inability to report a pain score, * history of a known neurological problem that changes pain perception, * history of cold related reactions (e.g. Raynaud's phenomenon, cold urticaria), * abnormal Allen's test

Locations (1)

Imam Khomeini hospital complex

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

puncture pain

30 seconds after ABG was performed, the patients would be asked about the puncture pain in verbal numerical pain scale.

Time frame: 30 seconds after ABG

Secondary Outcomes

Vapocoolant application pain

30 seconds after ABG was performed, the patients would be asked about the spray application pain in verbal numerical pain scale.

Time frame: 30 seconds affter procedure completion

number of puncture attempts

The number of ABG sampling attempts is recorded 30 seconds after procedure.

Time frame: 30 seconds after procedure

Data from ClinicalTrials.gov

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