Arterial Remodeling in Smokers

Klinik für Kardiologie, Pneumologie und Angiologie50 enrolled

Overview

Cigarette smoking is the most important modifiable cardiovascular risk factor leading to endothelial dysfunction and was suggested to impair arterial regeneration.The aim of the study was to investigate the effect of smoking on vascular response to transradial coronary angiography (TCA).

Study Type

OBSERVATIONAL

Enrollment

Conditions

FMD IMT Smoking

Interventions

smoke exposePROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * all subjects underwent a TCA Exclusion Criteria: * acute inflammation cardiac arrhythmia renal failure heart failure (NYHA II-IV) CRP \> 1 mg/dl malignant disease

Locations (1)

Division of Cardiology, Pulmonology and Vascular Medicine Duesseldorf,

Düsseldorf, North Rhine-Westphalia, Germany

Outcomes

Primary Outcomes

IMT hyperplasia

IMT is measured by high resolution ultrasound in the radial arteries.

Time frame: change in radials IMT after 6-14 month after a TCA

Secondary Outcomes

Endothelial function

Flow mediated dilatation (FMD)

Time frame: change in flow mediated dilatation after 10-14 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.