An Electronic Alert System for In-Hospital Acute Kidney Injury

University of Pennsylvania2,393 enrolled

Overview

This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention. The electronic alert will be in the form of a text page that will be sent to the covering clinician and unit pharmacist once per patient with AKI at the time lab results are uploaded. The investigators hypothesize that such an alert will improve outcomes in these patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

2,393

Conditions

Acute Kidney Injury

Interventions

AlertOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults \>=18 years * Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours. Exclusion Criteria: * Dialysis order within 24 hours of admission * Dialysis order prior to AKI onset * Initial creatinine \>=4.0mg/dl * Prior admission in which patient was randomized. * Nephrectomy during the admission * Admission to hospice service * Admission to observation status

Locations (1)

Hospital of the University of Pennsylvania

Phiadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Dialysis Within 7 Days

This metric will be sequentially ranked. The provision of acute dialysis therapy will be ranked as a more severe outcome than the worst relative change in creatinine and death will be ranked as a more severe outcome than dialysis.

Time frame: From start of AKI to 7 days later

Death

Time frame: 7 days of randomization

Relative Maximum Change in Creatinine

Time frame: 7 days of randomization

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.