A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery

Inclusion Criteria: The subject must meet all of the relevant criteria listed below to be enrolled in the study: 1. Subject must be ≥18 years of age. 2. Subject or subject's legally authorized representative must be willing give written informed consent. 3. Subject must be diagnosed with a ventral, incisional or first-recurrent incisional hernia. 4. Hernia size greater than 10cm2 and less than 250cm2 5. Subject must be willing to undergo ventral hernia repair and be able to undergo all other study procedures as outlined in this protocol. Exclusion Criteria: The subject must be excluded from study enrollment if any of the following criteria are met: 1. Subject's hernia is multiply recurrent. 2. CDC wound classification other than clean or clean-contaminated 3. The use of surgical repair as a bridge. 4. Patient has a contraindication to placement of mesh. 5. Concomitant procedures with wound classification other than clean 6. Subject has peritonitis. 7. Subject is on or suspected to be placed on chemotherapy medications during any part of the study. 8. Subject's body mass index (BMI) \>55 kg/m2. 9. Subject has cirrhosis, and/or ascites. 10. Subject is American Society of Anesthesiology Class 4 or 5. 11. Subject is known to be infected with human immunodeficiency virus (HIV). 12. Subject has known allergies to tetracycline or kanamycin. 13. Subject has a life expectancy of less than 2 years at the time of enrollment. 14. Subject has any condition in the opinion of the Investigator that would preclude the use of the study device, or preclude the subject from completing the follow-up requirements.