The investigators are trying to find out if Clopidogrel (Plavix) is as effective in hemodialysis patients as in patients not hemodialysed.
Cardiovascular disease is very frequent in hemodialysis patients. Lot of hemodialysis patients are on Clopidogrel (plavix). Their is some evidence that clopidogrel is not effective in hemodialysis as it is effective in patient without kidney problem. VerifyNow plavix is a machine that measure the ability of the blood to clot after giving plavix. We will collect blood from hemodialysis patients on plavix and check the ability of their blood to clot and thus indirectly measuring the efficacy of Plavix.
Study Type
OBSERVATIONAL
Enrollment
100
Staten Island University Hospital
Staten Island, New York, United States
Prevalence Of Plavix resistance
Plavix resistance is reported using the PRU values given by the VerifyNow machine. PRU is P2Y12 Reaction Units which is correlated with platelet aggregation.
Time frame: 1 day ( one study visit)
assess the risk factors for plavix resistance in the hemodialysis population
Coronary Artery Disease (CAD) is very common in dialysis patients. Treatment of CAD include medical therapy, stent placement and surgery. Since Plavix is a medication that is commonly used after stent placement, we would like to assess the efficacy of this medication in this patient population.
Time frame: 1 day (one study visit)
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