The Safety and Immunogenicity Research of Live Attenuated Varicella Vaccine After the 2 Doses Vaccination

Inclusion Criteria: -Participants from Shanxi province are between 1-12 years old are in good healthy determined through medical inquiry, physical examination, clinical judgment of the investor. Exclusion Criteria: 1. Having a fever (axillary temperature\>37.0℃) before enrollment; 2. Having a disease history of seizures, brain disease and the vaccination history of allergies and convulsions; 3. Antibiotics allergy; 4. Having a problem of intramuscular injection because thrombocytopenia or other blood coagulation disorder; 5. Having immunodeficiency or under immunosuppression therapy, radiation therapy; 6. Having respiratory diseases, acute infection, chronic disease and HIV infection; 7. Having systemic skin rash, skin tinea, herpes; 8. Chronic liver and kidney disease; 9. Heart disease, and severe hypertension; 10. Have received whole blood, plasma or immunoglobulin therapy 3 months before enrollment; 11. Have received other live attenuated vaccine vaccination in 30 days before enrollment; 12. Had been infected with Varicella virus and displayed symptom; 13. Have received one or two dose of Varicella vaccine before enrollment; 14. Congenital malformations, growth disorders such as Down's syndrome, diabetes, sickle cell anemia and nervous disorders 15. Guillain-barre syndrome 16. Thyroid resection history or thyroid disease treatment in the past 12 months; 17. Asthma 18. Have participated in other clinical research; 19. Have serious adverse reactions after vaccination, such as allergies, hives, breathing difficulties, angioneurotic edema.