Chronic kidney disease (CKD) is associated with high level of peripheral arterial disease (PAD). This could lead wounds, infections then amputations or deaths by impairment of the peripheral cutaneous perfusion. Medical therapies are presently unable to cure, but only slow down these disorders. Impact of exercise and lower extremity PAD rehabilitation is decreased by the significant inactivity of the chronic hemodialysis patients. Recently, many studies have shown several various favorable effects of the perdialytic physical activity. There is currently no data about effects of the perdialytic activity on the lower extremity perfusion. The aim of this clinical study is to show the impact of three months perdialytic cycling on the microcirculation, in chronic hemodialysis patients. Primary outcome will be the increase of cutaneous perfusion, assessed by measuring transcutaneous oxygen pressure (tcPO2) on about twenty patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
27
Cycling, in lying position, at a rate of thirty minutes per dialysis session (three a week), regardless of performance
Hôpital Edouard Herriot
Lyon, France
Increase of cutaneous lower extremity perfusion.
Time frame: TcPO2 will be performed at the inclusion and just after the end of the three month study period
Vascular assessment : Doppler and Index of systolic blood pressure
Time frame: At the inclusion and after the end of the three month study period
Related quality of life
Time frame: at the inclusion and after the end of the three month study period
Appetite (score)
Time frame: at the inclusion and after the end of the three month study period
Daily activity (Seven days pedometers)
Time frame: at the inclusion and after the end of the three month study period
Protein intake (n-PCR)
Time frame: at the inclusion and after the end of the three month study period
nutritional biological status (creatinin, albumin and transthyretin protein level)
Time frame: at the inclusion and after the end of the three month study period
strength (handgrip test)
Time frame: at the inclusion and after the end of the three month study period
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