The aim of the study is to train patients with Parkinson's Disease to increase activity in a brain area that is involved in the control of motor functions with the use of a technique called real-time fMRI neurofeedback (NF) along with regular physical exercise. This will be a randomised and controlled clinical trial to evaluate the benefits of a novel treatment. The investigators expect NF training along with physical exercise practise to better improve motor functions compared to physical exercise alone.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
School of Medicine, Cardiff University
Cardiff, Wales, United Kingdom
Change from Baseline in the 'Movement Disorder Society - Unified Parkinson's Disease Rating Scale' (MDS-UPDRS)
Time frame: Change from Baseline in the 'Movement Disorder Society - Unified Parkinson's Disease Rating Scale' (MDS-UPDRS) in 12 weeks
Change from baseline in the 'Parkinson's Disease Questionnaire 39' (PDQ-39)
Time frame: Change from baseline in the 'Parkinson's Disease Questionnaire 39' (PDQ-39) at 4 weeks
Change from baseline in the 'Parkinson's Disease Questionnaire 39' (PDQ-39)
Time frame: Change from baseline in the 'Parkinson's Disease Questionnaire 39' (PDQ-39) in 12 weeks
Change from baseline in the 'Actigraph'
Time frame: Change from baseline in the 'Actigraph' at 12 weeks
Change from baseline in the 'GaitRite'
Time frame: Change from baseline in the 'GaitRite' at 12 weeks
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