Older adults are at increased risk of high blood pressure and cognitive decline. High blood pressure itself also increases risk of cognitive decline. A particular type of blood pressure lowering drug (a calcium channel blocker(CCB)) may lower risk of dementia in younger adults but there is no clear evidence of it's impact in those \>=80. It is important that we know whether CCB use impacts on cognitive function in this age group. This study will examine the impact of antihypertensives on change in cognitive function with a particular focus on CCBs.
This study is an observational cohort study examining cognitive change in those participants taking antihypertensives and aged 80 and over and examining cognitive change in participants taking different types of antihypertensive medication.
Study Type
OBSERVATIONAL
Enrollment
337
The Kiltearn Medical Centre
Nantwich, Cheshire, United Kingdom
Ashfields Primary Care Centre
Sandbach, Cheshire, United Kingdom
Whitby Group Practice
Whitby, North Yorkshire, United Kingdom
South Axholme Practice
Epworth, Yorkshire, United Kingdom
Dr Moss and Partners
Harrogate, United Kingdom
Gale Farm Surgery
York, United Kingdom
Haxby Group Practice
York, United Kingdom
Change in Cognitive Function as Measured Using the Extended Mini Mental State Exam
The change in cognitive function measured using the extended mini-mental state exam (this is an extended screening test which assesses several areas of cognitive function, the scale is from 0-100, higher scores are better, those without cognitive impairment would be expected to score close to maximum)
Time frame: 12 months
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