One of the major side effects of surgery to remove the thyroid gland is transient (lasting for a short time) low calcium levels in the blood, or "hypocalcemia." Low calcium levels can cause symptoms such as numbness around the mouth, tingling or cramping in the hands and feet, severe muscle spasms, inability to breathe, or heart rhythm (heart beat) abnormalities. Severe symptoms are life threatening, so it is important to start the management of these symptoms in the hospital. Treating low calcium levels sometimes require patients to spend a few extra days in the hospital. The human body needs vitamin D to function and stay healthy. Vitamin D helps the body get the calcium needed to make strong bones and teeth. The purpose of this study is to determine if taking vitamin D before surgery to remove the thyroid gland affects whether or not you may have low calcium levels after your surgery and to test the hypothesis that those who are given the Vitamin D before surgery will have decreased hypocalcemia and a shortened hospital stay.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
67
1.0ug twice daily for 7 days before surgery
placebo pill taken twice daily for 7 days before surgery
University of Virginia
Charlottesville, Virginia, United States
Measure of Serum Calcium Levels
Serum calcium levels will be evaluated at routine intervals to identify incidences of hypocalcemia
Time frame: 2-5 days after surgery
Evidence of Hypocalcemia
Measuring hypocalcemia symptoms, requirements for IV calcium, and extended hospital stay
Time frame: 2-5 days after surgery
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