Implication of Left veNtricle Vortex Flow Guided aNticOagulation Therapy for preVenting Apical Thrombus Formation In Patients With Acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION Study

Yonsei University111 enrolled

Overview

Implication of left veNtricle vortex flow guided aNticOagulation therapy for preVenting Apical Thrombus formation In patients with acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION study

Study Type

OBSERVATIONAL

Enrollment

111

Conditions

Apical Thrombus Formation Acute Myocardial Infarction

Eligibility

Sex: ALLMin age: 30 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patient is ≥ 30 years old 2. Acute anterior wall myocardial infarction showing akinetic or dyskinetic apical wall motion abnormalities on an initial transthoracic echocardiogram 3. Left ventricular ejection fraction less than 40% Exclusion Criteria: 1. Prior history of myocardial infarction 2. Chronic medication with Coumadin 3. Contraindication of contrast echocardiography 4. Significant atrial or ventricular arrhythmia 5. Valvular heart disease more than moderate degree 6. Decompensated heart failure 7. Very poor echo window, which cannot evaluate the presence of apical thrombus

Locations (1)

Severance cardiovascular hospital

Seoul, Seoul, South Korea

Outcomes

Primary Outcomes

Apical thrombus formation in echocardiography

Evaluate and compare the incidence of thrombus formation in high risk group (Vortex depth \< 0.45) and low risk group (Vortex Depth ≥ 0.45)

Time frame: 30 days after initial echocardiography

Data from ClinicalTrials.gov

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