Single and Multiple Dose Study in Japanese Subjects

Inclusion Criteria: * Able to understand the study procedures and the risks involved, and willing to provide written informed consent before the first study related activity. * Healthy adult male subject born in Japan. * Subject has parents and grandparents who are Japanese. * Subject is in possession of a valid Japanese passport. * All laboratory parameters should be within normal limits or considered not clinically significant by the investigator. * Screening serum urate level ≥ 4.5 mg/dL. * Subject is free of any clinically significant disease that requires a physician's care and/or would interfere with study evaluations or procedures. * Subject has a normal or clinically acceptable physical examination. * Subject has no clinically relevant abnormalities in blood pressure, heart rate, and body temperature, per the Investigator's judgment. Exclusion Criteria: * Positive serology to human immunodeficiency virus (HIV-1 or HIV-2). * Positive test for active hepatitis B or hepatitis C infection. * History or suspicion of kidney stones. * Undergone major surgery within 3 months prior to Day 1. * Exposed to an investigational drug (or a medical device) within 30 days or 5 half-lives of the investigational drug (whichever is longer) prior to Day 1 or is currently participating in another study of an investigational drug (or medical device). * Prior exposure to RDEA3170.