Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.

Inclusion Criteria: * Patients ≥ 18 years with a minimum weight of 40 kg. * Microbiological Isolation of S. aureus susceptible to meticillin. * Start antibiotic treatment with drugs active against S. aureus within 72 hours from the onset of clinical manifestations. * Women of childbearing potential, negative pregnancy test negative serum or urine or statement is not pregnant. * Prescription prior treatment must be independent and decoupled patient inclusion in the study, corresponding exclusively to clinical practice. Exclusion Criteria: * Polymicrobial bacteremia. * Neutropenic patients. * Patients addicted to intravenous drugs. * Patients with malignancies with expected survival less than 6 months. * Severe allergy to beta-lactams or fluoroquinolones. * Creatinine clearance \<20ml/min. * Need for hemodialysis, peritoneal dialysis or plasmapheresis. * Clinical signs of deep infection in the first five days of treatment (mucocutaneous lesions suggestive of IE, embolic events, suppurative thrombophlebitis. * Predictors of bacteremia complicated: * Positive blood cultures for 48-96 hours of starting treatment antistaphylococcal * Clinical Instability * Signs of sepsis or persistent fever at day 4 of treatment * Existence of valvular or vascular prosthetic joints, vascular catheter not removed within three days * Heart disease predisposing to endocarditis. * Patients presenting diagnosis concomitant infection by another organism. * Pregnant or breast-feeding. * Patients with epilepsy. * Patients with a history of tendon disorders related to fluoroquinolone administration. * Not have signed informed consent.