Pharmacokinetic Drug Interaction Between YH4808 and Diclofenac

Inclusion Criteria: * healthy male age 20 to 45 over 55kg with Ideal body weight(IBW) * No clinically important abnormal physical findings at the screening examination * Subject who has no congential, chronic disease and disease symptoms in medical examination result * Subject who is judged to be eligible by principal inverstigator or sub-investigator according to various reasons includiong ther abnorminal test results(clinical laboratory test, 12-lead GCG etc) * Ability to communicate well with the inverstigator and to comply with the requremetns of the entire study * Willingness to give written informed consent(prior to any study-related procedures beinging performed) and to be able to adhere to the study restrictions and examination schedule Exclusion Criteria: * Suject who has history or presence of clinically significant diseases in liver, kidney, gastrointestinal tract, nervous system, respiratory system, endocrine system, blood tumor, cardiovascular, urinary system, and mental disorder * Subject who is hypersensitive to components contained in YH4808 or declofenac or related drug(ex. rebamipide, revaprazan, NSID etc) * Medical history of gastrointestinal disease or acid restraining surgery, gastric/ esophagus surgery(excluding appendectomy, hernia surgery) * Subject who has history of drug dependence or using that drug * Subject who had taken usual dose of any prescription durgs within 14 days before the treatment or who had used usual dose of OTC drugs within 7 days before the treatment * Subject who participated in antoher clinical trial within 2 monthes before enrolling in this study * subject who donated whole blood within 2 months or component blood within 1 month before the treatment * Subject who drank over 21unit/week(1 unit= 10g of alcohol) or were not able to refrain from drinking alcohol during study days * Subject who stopped smoking within 3 months before the treatment or detected cotinine in urine test * Subject with clinically significant observations considered as unsuitable based on medical judgment by the investigators