PKPD Study of Ticagrelor and Prasugrel in Healthy Korean Males

Inclusion Criteria: 1. male aged 19 - 45 years at screening visit 2. body weight at least 60 kg at screening visit 3. body mass index 18 - 30 kg/m2 4. SBP 90 - 149 mmHg and DBP 60 - 99 mmHg and pulse rate(beat per minute) 45 - 100 at screening visit Exclusion Criteria: 1. any history of or having any clinically significant abnormalities 2. any gastrointestinal disorder having impact on absorption of study drug 3. any history of hypersensitivity of ticagrelor or prasugrel or compounds related study drugs 4. any history of taking original medicines within 30 days before dosing or history of taking prescribed drug within 14 days before dosing or history of taking OTC drug within 7 days before dosing 5. any history of taking other study drug within 60 days before dosing 6. any history of whole blood transfusion within 60 days before dosing or history of blood elements transfusion or history of heaving been transfused within 30 days before 30 days 7. any history of taking metabolic inducer or inhibitor 8. overuse (caffeine: \> 5 units/day , alcohol: \> 21 units /week, smoking: \> 10 cigarettes/day) 9. positive serology testy(Hbs antigen, HIV, Hepatitis C virus, Syphilis) 10. any abnormality in clinical laboratory tests result or any ECG finding considered to be inadequate by investigator