Post-extubation Boussignac CPAP System in Adults With Moderate to Severe Obstructive Sleep Apnea

Queen's University48 enrolled

Overview

The purpose of this study is to assess the efficacy of the Boussignac positive airway pressure system (a mask) applied immediately following post-operative extubation in improving lung function in patients with obstructive sleep apnea (OSA). Assessments will be done before surgery and then at 1, 2 and 24 hours following extubation and will be compared to standard care for perioperative airway support. The study aims to give a broader and more inclusive picture (than the current literature) in terms of whether the Boussignac CPAP system should be considered for utilization by anesthesiologists caring for surgical patients with OSA.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Obstructive Sleep Apnea (OSA)

Interventions

Is a continuous positive airway pressure (CPAP) system marketed in Canada and the US for the treatment of Obstructive Sleep Apnea. The main difference is that this system is portable wheres the standard hospital CPAP is not. This allows for the application immediately post-extubation.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: -\> 18 years of age * ASA II-IV * Previous diagnosis of moderate to severe obstructive sleep apnea * diagnosed via polysomnography * BMI \< 40 * scheduled for an abdominal or peripheral surgical procedure requiring endotracheal intubation and admission to hospital Exclusion Criteria: * BMI \> 40 * Age \<18 years * inability to provide signed informed consent * intra-thoracic * head or neck surgery * contraindication for immediate post-extubation application of CPAP * not expected to be eligible for timely extubation following the surgical procedure

Outcomes

Primary Outcomes

percent forced vital capacity %(FVC)

%FVC will be assessed 24 hours postoperatively in patients who received the Boussignac CPAP mask immediately post-extubation and these values compared to those of patients who received the standard-of-care treatment for obstructive sleep apnea

Time frame: 24 hours postoperatively

Secondary Outcomes

% forced expiratory volume in 1 second (FEV1)

Time frame: 1,2 and 24 hours post-operatively