Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive Disorder

Inclusion Criteria: * Male or Female outpatients between 12-17 years of age * Primary diagnosis of major depressive disorder (MDD) * Children's Depression Rating Scale-Revised (CDRS-R) score of 40 or greater * Clinical Global Impressions-Severity (CGI-S) score of 4 or greater Exclusion Criteria: * Current (past 3 months) principal Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision (DSM-IV-TR) based diagnosis of an axis disorder other than major depressive disorder (MDD) that is the primary focus of treatment. * History of suicidal behavior, or requires precaution against suicide * Not generally healthy medical condition * Seizure disorder