The purpose of this study is to evaluate the value of positron emission tomography/computed tomography in various inflammatory conditions caused by bacterial infection or vasculitis. Glucose analog FDG is sensitive to detect inflammation foci but we hypothesize that other imaging agents such as PK11195 and Ga-citrate may have added value in certain applications.
The purpose of this study is to evaluate the value of PET/CT in various inflammatory conditions caused by bacterial infection or vasculitis. Our aim is to: 1. investigate whether FDG (18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose) PET/CT and 68Ga-(Gallium-68) citrate PET/CT enable the early and accurate detection of metastatic infection foci in Staphylococcus aureus bacteremia. 2. study the usefulness of FDG PET/CT in detection of endovascular infection in bacteremia caused by Salmonella spp. 3. find an optimal FDG PET/CT protocol for detection of infectious endocarditis and metastatic infection foci related to endocarditis. 4. study the value of FDG PET/CT in the diagnosis of infection of pacemaker or implantable cardioverter defibrillator. 5. investigate the usefulness of FDG PET/CT, 68Ga-citrate PET/CT, and 11C- (carbon-11) translocator protein ligand (PK11195) PET/CT in diagnosis of vasculitis and in imaging of the magnitude of the vascular changes.
Study Type
OBSERVATIONAL
Enrollment
117
positron emission tomography/computed tomography
Turku University Hospital
Turku, Finland
Detection of infection or vasculitis in PET images
Time frame: within 1 week after starting the treatment
Standardized uptake value of PET imaging agent at the site of infection or vasculitis
Time frame: within 1 week after starting the treatment
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.