The investigators want to test during anesthesia the feasibility of a closed-loop automated fluid replacement system using cardiac output monitoring as the input value.
The optimization of the cardiac output is an important goal during anesthesia to decrease the postoperative morbidity, mortality and the care costs. We want to test if the closed-loop fluid administration is feasible. Two groups will be compared. In all cases: * anesthesia will be provided by a closed-loop which aim is to maintain bispectral index between 40 and 60 using propofol and remifentanil. This method permits to have similar depths of anesthesia in all cases. * cardiac output will be continuously monitored by LidCO. In one group, fluid replacement is decided by the physician; in the other, fluid replacement is automated using a closed-loop system.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
2
Hopital Foch
Suresnes, France
Mean cardiac output index during the surgery
Time frame: One day after anesthesia
Time before reaching maximizing cardiac output
Time frame: One day after anesthesia
Volume of fluid replacement during surgery
Time frame: One day after anesthesia
cardiac index during the surgery
Maximum and minimum values during the surgery
Time frame: One day after anesthesia
arterial hypertension
Number of events treated
Time frame: One day after anesthesia
Dysfunction of the closed-loop fluid device
Time frame: One day after anesthesia
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.