This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass). Specifically, researchers want to: * Examine the efficiency of protein intake after exercise on muscle mass and physical abilities; * Examine the impact of exercise and proteins on blood lipids (LDL cholesterol, HDL cholesterol, total cholesterol and triglycerides); * Examine the impact of exercise and proteins on liver enzymes; * Examine the impact of exercise and proteins on a hormone that controls hunger; * Evaluate the program's impact on the ability of the body to produce energy. All participants are exercising (resistance training) and ingest one of the 3 different sources of proteins, immediately after training: * Milk proteins (from milk beverage) * Essential amino acids (added to a soya beverage) * No protein (rice beverage - control group) Our hypothesis is that proteins from milk will induce a gain in muscle mass and physical function equivalent to the essential amino acids (EAA). We anticipate that both milk proteins and EAA will be both superior to control group. This would represent an interesting finding since milk is more accessible, palatable and cheaper than essential amino acids commercial mix.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
41
All group will exercise 3x/week. Each session of resistance training will last 60min. and will target main muscular groups.
Centre de recherche sur le vieillissement
Sherbrooke, Quebec, Canada
Muscle mass
Time frame: At baseline and post intervention (17th week)
Relative strength
Time frame: At baseline and post intervention (17th week)
Blood markers of inflammation
Plasmatic IL-6 anf TNF-alpha
Time frame: At baseline and post intervention (17th week)
Plasma Lipid profile
Apolipoproteins (Apo-AI, Apo-AII, Apo-B); Total cholesterol, HDL, LDL and triglycerides.
Time frame: At baseline and post intervention (17th week)
Plasma creatinine
Blood marker on renal function will be assessed to ensure the safety of the supplementation of protein intake on renal function in sarcopenic men.
Time frame: At baseline, mid (8th week) and post intervention (17th week)
Blood markers of fatty liver
Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Gamma-glutamyltransferase (GGT) and Alkaline phosphatase (ALP).
Time frame: At baseline and post intervention (17th week)
extracellular HSP72
Time frame: At baseline and post intervention (17th week)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.