National, Multicenter PMS Study "Patient Reported Outcome" in Breast Reconstruction Following Mastectomy With TiLOOP Bra

Inclusion Criteria: The TiLOOP®Bra is designed to assist oncologically indexed skin sparing mastectomy or subcutaneous mastectomy with preservation of the nipple-areola-complex during primary breast reconstruction, secondary breast reconstruction or corrective breast surgery. Patients shall be included if they meet all of the following criteria: Clinical Criteria (reason): * women with indication of prophylactic operation or oncoplastic operation with support of a mesh implant * women with histologically confirmed breast cancer or precancerosis or genetic pre-existing conditions with increased risk of breast cancer or with a family history * the health of women must comply with ECOG (Eastern Cooperative Oncology Group) performance status 0-2 Study-related inclusion criteria - Legal reasons: * Patient is mentally able to understand the nature, aims, or possible consequences of the clinical investigation * Patient information has been handed out and all written consents are at hand. * Patient is between 18 and 70 years old. Exclusion Criteria: Patients must be excluded if any of the following conditions exist or cannot be excluded: Device-related exclusion criteria (contraindications): Pathological or physical condition precluding such as: * Pregnancy or breast-feeding patients * Known intolerance to the mesh-implants under investigation. Study-related exclusion criteria - Medical reasons: * metastatic breast cancer * medicamentous regulated diabetes with blood sugar level \>250 * inadequate bone marrow function with neutrophil granulocytes \<1500 and blood plates \< 10000/µl * patient with known contraindication to mesh-implants or plastic-reconstructive breast operations Study-related exclusion criteria - Legal reasons: * Lack of written patients informed consent. * Lack of patient compliance regarding data collection, treatment or follow-up investigations in the scope of the protocol. * Patient is institutionalized by court or official order (MPG§20.3). * Participation in another operative clinical investigation. It is thought that the study-related exclusion criteria will not significantly influence the sample of the population under investigation.