Recently, a clinical trial showed that the use of lumbar drains compared to ventricular drain in patients suffering from subarachnoid hemorrhage resulted in less delayed ischemic neurological deficits but failed to show a clinical benefit after 6 months. The underlying assumption was, that the cerebrospinal fluid (CSF) obtained from lumbar drains has a higher concentration of blood than CSF from lumbar drains. The investigators decided to test this assumption. In this study, the investigators will randomize patients to either placement of a ventricular or a lumbar drain and analyze the CSF drainage on a daily basis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Department of Neurosurgery, Odense University Hospital
Odense, Denmark
RECRUITINGAccumulated Hb and bilirubin in CSF drainage
Time frame: From drain placement to removal, in average 10 days.
placement of a ventriculoperitoneal shunt
Time frame: participants will be followed for the duration of hospital stay, in average 3 weeks
Lindegaard ratio (TCD) > 3
Time frame: the participants will be followed for the duration of hospital stay, in average 3 weeks
clinical signs of vasospasms
Time frame: The participants will be followedd for the duration of hospital stay, in average 3 weeks
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