A two month intervention trial assessing the effect of Vetal Laban containing L. acidophilus on enhancing functional bowel wellbeing among subjects with irritable bowel syndrome (IBS).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
62
Dairy product with probiotic
Dairy product without probiotic
King Fahd Medical City
Riyadh, Saudi Arabia
King Khalid University Hospital
Riyadh, Saudi Arabia
change in functional bowel symptoms
Validated questionnaire
Time frame: week 0, 4, 8, 12 and 16
change in adequate relief of bowel symptoms
Weekly question
Time frame: weekly from week 4 to week 12
change in stool defecation frequency
Validated scale
Time frame: week 0, 4, 8, 12 and 16
change in stool microbiota
molecular analyses
Time frame: week 4, 8, 12 and 16
change in prevalence of adverse events
Recording of adverse and serious adverse events
Time frame: continuous from week 0 to 16
change in stool consistency
Validated scale
Time frame: week 0, 4, 8, 12 and 16
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