Utility of Psychosocial Intervention in Improving Outcome for Methadone-exposed Infants and Their Mothers

Dr. Henry Akinbi113 enrolled

Overview

Opiate drug abuse/addiction is a significant co-morbidity in pregnancy. Opiate maintenance program enhances the outcome of pregnancies for the mother and the infant. Our objective was to assess if provision of structured psychosocial support in addition to methadone maintenance program adds incremental benefits with regards to the outcome of pregnancy.

Study Type

OBSERVATIONAL

Enrollment

113

Conditions

Neonatal Abstinence Syndrome

Interventions

Structured psychosocial interventionBEHAVIORAL

This is retrospective analysis of two groups of opiate-addicted pregnant women: 1) Pregnant women in methadone maintenance program 2) Pregnant women in methadone maintenance program AND structured psychosocial intervention

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Positive Methadone tox screen * Received care at Good Samaritan Hospital in Cincinnati * Delivered at Good Samaritan Hospital Exclusion Criteria: * Twin gestation * Sever congenital anomalies * Conditions requiring transfer to quaternary hospital

Locations (1)

Good Samaritan Hospital

Cincinnati, Ohio, United States

Outcomes

Primary Outcomes

Percentage of newborns in each group that required pharmacological treatment for neonatal abstinence syndrome

Infants delivered to mothers that are maintained on methadone are at risk for neonatal abstinence syndrome. Psychosocial support is provided to pregnant women in methadone maintenance program to impact the outcome of the infants. The percentage of infants requiring pharmacotherapy would be expected to be reduced by the addition of psychosocial intervention to methadone maintenance program.

Time frame: Birth until discharge

Secondary Outcomes

Gestational age at which the infants were delivered.

Addiction of pregnant women to opiate drugs is associated with preterm delivery. The gestational ages of infants delivered to women in the two groups will be compared for statistically significant differences.

Time frame: Gestational age at delivery.

Percentage of infants that are small for gestational age.

Addiction to opiates is associated with fetal growth restriction. This study compared the proportion of infants who are \<90th percentile for gestational age in both groups.

Time frame: Gestional period.

Anthropometric measurements at birth

Differences between the mean birth weight, Length and head circumference at birth were compared between the two groups.

Time frame: Measurements at birth.

Data from ClinicalTrials.gov

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