The Dose of Sugammadex for Rapid Reversal of Profound Neuromuscular Block in Young and Elderly Patients

Severance Hospital44 enrolled

Overview

To find out the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound rocuronium-induced neuromuscular block in young and elderly adult patients.

A previous study reported that elderly patients required a longer time to recover from rocuronium induced neuromuscular block compared to younger patients. Therefore, the aim of this study is to find out the dose of sugammadex for rapid recovery from profound neuromuscular block in young and elderly adult patients.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Anesthesia Recovery Period, Neuromuscular Blockade

Interventions

SugammadexDRUG

The dose of sugammadex

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 20-40 years or ≥70 years ASA class I-II patients who received surgery less than 2 hours. Exclusion Criteria: * anticipated difficult intubation * neuromuscular, hepatic or renal disorders * drug allergy * body mass index \>30 kg/m2 or body mass index \<18 kg/m2 * emergency surgery

Locations (1)

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine

Seoul, South Korea

Outcomes

Primary Outcomes

The dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound neuromuscular block

Time frame: 2 hour

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.