Maintenance Transcranial Electrical Stimulation for Depression

The University of New South Wales25 enrolled

Overview

Transcranial electrical stimulation (TES) techniques offer a novel treatment approach for depression and have shown promising efficacy. However, there is no published data to date on their effectiveness as a maintenance treatment. This study will investigate ways of using TES as a maintenance treatment to prevent relapse in depression.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Major Depressive Disorder Bipolar Disorder

Interventions

Transcranial electrical stimulationDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All participants will be ≥ 18 years old. * Participants must have experienced a significant clinical response, defined as ≥ 50% decrease from baseline scores on the Montgomery Asberg Depression Rating Scale (MADRS). Exclusion Criteria: * Inadequate response to acute trial of TES. * Suicidality. * Clinically defined neurological disorder or insult. * Metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites. * Pregnancy (women of childbearing age will be asked to undergo a urine pregnancy test prior to starting the study). * Concurrent long acting benzodiazepines, ritalin or dexamphetamine medication. * Treatment for depression is changed during months 3-9 of the trial.

Locations (1)

Black Dog Institute / University of New South Wales

Randwick, Sydney, New South Wales, Australia

Outcomes

Primary Outcomes

Montgomery Asberg Depression Rating Scale for Depression (MADRS)

Time frame: 9 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.