To compare efficacy and safety of initial combination therapy of Gemigliptin versus Sitagliptin or Glimepiride with Metformin on Glucose Variability(MAGE, Glucose SD) in Patients With Type 2 Diabetes Mellitus.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
69
Severance hospital
Seoul, South Korea
Mean Amplitude Glycemic Excursion
Time frame: Change of MAGE at Week 12 from baseline
Glucagon
Time frame: Change of Glucagon at Week 12 from baseline
Active GLP-1
Time frame: Change of Active GLP-1 at Week 12 from baseline
CRP
Time frame: Change of CRP at Week 12 from baseline
Nitrotyrosine
Time frame: Change of nitrotyrosine at Week 12 from baseline
Glycated albumin
Time frame: Change of glycated albumin at Week 4 from baseline
Fructosamine
Time frame: Change of fructosamine at Week 4 from baseline
Glucose Standard Deviation in CGMS data
Time frame: Change of Glucose SD at Week 12 from baseline
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