Vitamin D + Telaprevir + Peginterferon + Ribavirin for of Hepatitis C Genotype 1

Inclusion Criteria: * Chronic Hepatitis C genotype 1 infection * Treatment naïve * Age \>18 years * Agree to genetic testing Exclusion Criteria: * Liver disease other than from hepatitis C * HCV infection with mixed genotypes * Decompensated liver disease * AFP\>100ng/ml. * Known HIV infection * Serum 25(OH)D less than 12ng/ml or greater than 30ng/ml * Regular vitamin D supplement use * Regular calcium supplement use * Refusal to abstain from vitamin D supplementation * Current or past history of kidney stones * Current use of any of the prohibited medications listed in section 5.5 and the INCIVEK® package insert. * Need for therapeutic vitamin D or calcium (e.g. treatment for osteoporosis, osteomalacia, hyperparathyroidism etc.), in the opinion of the investigator * Significant substance abuse within the past 6 months, * Suicidal attempt in the past 10 years or suicidal ideation in past 3 months, or any other psychiatric condition that the investigator deems would make a subject unsuited for treatment with peginterferon or ribavirin. * Confirmed or suspected malignancy, or history of malignancy within the past 3 years (except treated basal cell carcinoma of the skin or in situ carcinoma of the uterine cervix) * Any autoimmune disease not easily controlled (in the opinion of the investigator) * Any condition resulting in malabsorption ( * Poorly controlled thyroid disorder, or diabetes mellitus (HbA1c \> 9) * Glomerular diseases (e.g., glomerulosclerosis or glomerulonephritis) associated with a serum creatinine \>1.5 times the upper limit of normal * Current or history of any clinically significant cardiac abnormalities/dysfunction (eg, angina, congestive heart failure, myocardial infarction, pulmonary hypertension, complex congenital heart disease, cardiomyopathy, significant arrhythmia) including current uncontrolled hypertension or history of use of antianginal agents for cardiac conditions (Inclusion will be considered if clearance by a cardiologist is obtained.) * Receipt of an investigational drug within the past 30 days * Females who have a positive pregnancy test at the time of screening, are breastfeeding or who anticipate pregnancy within the next 18 months, or men with pregnant partners * Lack of agreement from subject to use two forms of acceptable contraception * History or other evidence of any significant illness which, in the opinion of the investigator, would make the patient, unsuitable for the study * Laboratory Exclusions Hemoglobin: \<12gm/dl male or female Neutrophil: \<1,200/mm3 Platelets: \<90,000/mm3 INR: \>1.5 Albumin: \<3.2gm/dl Total Bilirubin: \>2.0mg/dl HbA1c: \>9.5% Serum Creatinine: \>1.5 times the upper limit of normal Serum Calcium Within local laboratory normal range Parathyroid hormone (PTH) \<10 or \>55 pg/mL