Multiple sclerosis is a neurological disease that can affect lung function and cough efficacy. This pilot study will examine whether the lung volume recruitment technique can slow down the decline in lung function and cough.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
35
Inflation of the lungs to their maximal insufflation capacity by the consecutive delivery, by a manual resuscitator in this study, of volumes of air that are held with a closed glottis
The Ottawa Hospital
Ottawa, Ontario, Canada
RECRUITINGHôpital Charles-LeMoyne
Greenfield Park, Quebec, Canada
RECRUITINGRate of decline of FVC (forced vital capacity)
Time frame: up to 9 months
Rate of decline of peak cough flow
Time frame: baseline, 2, 4, 6 and 9 months
Change from baseline in FVC at 2, 4, 6 and 9 months
Time frame: baseline vs 2, 4, 6 and 9 months
Change from baseline in peak cough flow at 2, 4, 6 and 9 months
Time frame: baseline vs 2, 4, 6 and 9 months
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