Inert Gas Rebreathing in Ventilated Patients

Universitätsmedizin Mannheim50 enrolled

Overview

Measuring hemodynamic parameters in ventilated patients is important yet still complicated to perform. Inert gas rebreathing (IGR) showed promising results when being compared to other invasive as well as non-invasive techniques for the measurement of cardiac output. The aim of our study is to evaluate the feasibility of IGR in ventilated patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sepsis Respiratory Failure Heart Failure Renal Failure

Interventions

non-invasive determination of cardiac outputDEVICE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age 18 - 80 years * mechanically ventilated patient * existing PiCCO arterial line Exclusion Criteria: * FiO2 \> 60% (fraction of inspired oxygen) * PEEP \> 10 mmHg (positive end-expiratory pressure) * SO2 \< 90% (oxygen saturation ) * Systolic blood pressure \< 90 mmHg * Heart rate \> 150 bpm * APRV (airway pressure release ventilation) * ICD (implantable cardioverter defibrillator) / pace maker * \[ Anaesthetic Conserving Device (Anaconda) \]

Locations (1)

Universitätsmedizin Mannheim

Manheim, Baden-Wurttemberg, Germany

Outcomes

Primary Outcomes

cardiac output

Determination of cardiac output using invasive pulse contour analysis (PiCCO) and non-invasive inert gas rebreathing (Innocor)

Time frame: 1 day

Data from ClinicalTrials.gov

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