Influence of Trigger Threshold on Controlled Twitch Mouth Pressure

N/ACompletedNCT01891942

Guangzhou Institute of Respiratory Disease30 enrolled

Overview

The inspiratory pressure trigger is essential when assessing the twitch mouth pressure (Tw Pmo) for avoiding glottic closure. However, the difference in inspiratory pressure trigger threshold may influence the values of Tw Pmo. We sought to determine the trigger threshold for healthy subjects and COPD patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

COPD Healthy

Interventions

twitch by magstimPROCEDURE

Eligibility

Sex: MALEMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Clinical diagnosis of COPD 2. Stable with no episodes of exacerbation within the previous 2 months 3. Do not currently being treated with oral corticosteroids Exclusion Criteria: 1. Not stable within the previous 2 months. 2. Patients with COPD were currently being treated with oral corticosteroids

Locations (1)

Guangzhou Institute Respiratory Disease

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

Twitch mouth pressure

Time frame: 2 weeks

Secondary Outcomes

Twitch oesophageal pressure

Time frame: 2 weeks

Data from ClinicalTrials.gov

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