To develope nerve sparing radical hysterectomy for treatment of cervical cancer to minimize the complication of radical hysterectomy and to maximize quality of life and to evaluate the feasibility and efficacy by prospective randomized trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
146
Nerve sparing radical hysterectomy 1. sparing hypogastric nerve 2. sparing pelvic splanchnic nerve ad pelvic plexus in cardinal ligament 3. sparing distal part of hypogastric nerve and vesical branch of pelvic splanchnic nerve
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center
Seoul, South Korea
RECRUITINGIncidence of bladder dysfunction after surgery
Remove foley catheter and measure the residual urine volume Measure how long it took to be residual urine volume under 50 mL
Time frame: 5 days after the surgery
rectal & anal function after surgery
Time frame: 6, 12 months after surgery
Sexual function
Time frame: 6, 12 months after surgery
Quality of life
Time frame: 6, 12 months after surgery
operative time
Time frame: immediately after surgery
amount of bleeding in operation
Time frame: immediately after surgery
frequency of blood transfusion
Time frame: within 1 week after surgery
amount of blood transfusion
Time frame: within 1 week after surgery
postoperative complication
Time frame: within 1 month after surgery
time from surgery to return to work
Time frame: within 1 month after surgery
management cost
Time frame: within 1 week after surgery
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size of resected parametrial tissue
Time frame: immediately after surgery
2year disease free survival
Time frame: 2 year after treatment