Multistimulation Group Therapy for Alzheimer's Disease

Fondazione Don Carlo Gnocchi ETS60 enrolled

Overview

Our previous findings support the notion that group activity program, based on cognitive stimulation, recreational-occupational activities and physical-psychomotor exercises, can lead to an improvement in behavioral aspects for people with Alzheimer's Disease (AD). The purpose of this study is to clarify the efficacy of a rehabilitation program in outpatients affected by AD in mild to moderate stages.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

SINGLE

Enrollment

Conditions

Alzheimer's Disease

Interventions

Multidimensional stimulation group therapyOTHER

The MST program involved three levels of treatment. The first level was focused on PWA, the second level involved the caregiver, while the third one the dyad PWA-caregiver.

Eligibility

Sex: ALLMin age: 65 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of possible/probable AD * mild to moderate stage of AD (MMSE score of 15 - 24)and CDR score of 1-2 * range years in age (65-85) and in school attendance (5-17) * right handed Exclusion Criteria: * severe aphasia (Token test score \< 20) * severe auditory and/or visual loss * overt severe behavioral disturbances (delusions, hallucinations, agitation) * recent (three month before the MST) introduction or dose modification of the following pharmacological treatments: cholinesterase inhibitor, memantine, antidepressant or antipsychotic drugs.

Locations (1)

IRCCS, S Maria Nascente, FOndazione don Gnocchi

Milan, Italy

Outcomes

Primary Outcomes

Change from baseline in behavioral level

Neuropsychiatric Inventory scale

Time frame: Baseline, 10ws, 22ws

Change from baseline in cognitive level

ADAS cog scale

Time frame: Baseline, 10ws, 22 ws

Change from baseline in quality of life

SF36 questionaire

Time frame: baseline, 10ws,22 ws

Data from ClinicalTrials.gov

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