This study will test the potential of two techniques using light properties of adipose tissue to diagnose crown-like structures and inflammation to be compared with pathologic examination of adipose tissue biopsies from ongoing clinical studies.
Adipose tissue (fat) inflammation is emerging as an important harbinger of disease development including Type 2 diabetes, heart disease and potentially cancer. The hallmark feature of adipose tissue inflammation is the crown-like structure, a dying fat cell surrounded by immune cells attempting to clear the damage. Current methods for detecting adipose tissue inflammation rely on invasive procedures such as fat biopsies. We propose developing methods that use the light reflection properties of inflamed adipose tissue as a potential non-invasive method to detect adipose tissue inflammation.
Study Type
OBSERVATIONAL
Enrollment
14
Fat biopsy
The Rockefeller University
New York, New York, United States
Classification of adipose tissue as healthy or inflamed by Raman Spectroscopy
Classification of adipose tissue as healthy or inflamed by Raman Spectroscopy
Time frame: 1 day
Steady state oxygenation at the site of tissue biopsy by Diffuse Reflectance Spectroscopy
Steady state oxygenation at the site of tissue biopsy by Diffuse Reflectance Spectroscopy
Time frame: 1 day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.