This study is aimed to evaluate the effect of renal denervation to decreasing blood pressure and left ventricle remodeling progression in patients after acute coronary syndrome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
The treatment catheter is introduced into each renal artery and is applied discrete, radiofrequency ablations lasting up to 2 min each and of 8 watts or less to obtain up to six ablations separated both longitudinally and rotationally within each renal artery. During ablation, the catheter system monitored tip temperature and impedance, altering radiofrequency energy delivery in response to a predetermined algorithm. After the procedure the control arterial angiogram should be done.
Beta-blockers. Optimal mediсal therapy will be assigned according to ACS and STE guidelines.
ACE inhibitors. Optimal mediсal therapy will be assigned according to ACS and STE guidelines.
State Research Institute of Circulation Pathology
Novosibirsk, Russia
RECRUITINGcardiovascular death
Time frame: 1 year
myocardium infarction
Time frame: 1 year
stroke
Time frame: 1 year
repeat revascularization
Time frame: 1 year
blood pressure changes
Time frame: 1 year
CCS and NYHA
Time frame: 1 year
heart rhythm disturbances
Time frame: 1 year
intima-media index
Time frame: 1 year
IVS thickness
Time frame: 1 year
restenosis
Time frame: 1 year
diastolic disfunction
Time frame: 1 year
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