Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis

N/AWithdrawnNCT01903668

Centre Hospitalier Universitaire Dijon

Overview

Step 1: Identification and characterisation of the TREM1L protein from samples already available characterised at the hospital Central of Nancy Step 2: Study of the isoforms of TREM1L in correlation with the prognosis of sepsis, Step 3: implementation of assay methods for TREM1L (ELISA or SUPRA MS) Step 4: Validation of assays for TREM1L and its isoforms in a larger number of subjects (inclusion of samples from Dijon CHU and Besançon CHU)

Study Type

OBSERVATIONAL

Conditions

Sepsis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients hospitalised in a Medical Intensive Care unit whatever the reason * written informed consent obtained Exclusion Criteria: * patients less than 18 years old or under guardianship, persons without national health insurance.

Outcomes

Primary Outcomes

plasma concentrations of sTREM-1

Time frame: baseline

Data from ClinicalTrials.gov

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