Longitudinal Study of Quality of Life and Activity in Systemic Lupus Erythematosus

N/ACompletedNCT01904812

Centre Hospitalier Universitaire Dijon356 enrolled

Overview

Systemic lupus erythematosus is a complex disease whose evaluation in everyday practice and in clinical research requires several aspects to be taken into account, in particular the impact of disease activity on quality of life. To date, the effect of systemic lupus on quality of life has only been described using generic questionnaires. Among the specific questionnaires for systemic lupus, the LupusQol, which has been validated in French, shows interesting psychometric properties. The determinants of quality of life specifically related to the disease are still unknown and could be studied using a longitudinal cohort thanks to the French version of the LupusQol.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

356

Conditions

Lupus Erythematosus

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \- Patients meeting ACR 1997 classification criteria for systemic lupus erythematosus. * Patients able to understand written and spoken French. * Patients aged from 18 to 75 years * Patients who have received written and oral information about the research. Exclusion Criteria: * \- Patients aged less than 18 years * Patients aged more than 75 years * Severe mental retardation Any impairment of abilities to understand that make self-evaluation impossible

Outcomes

Primary Outcomes

data for quality of life and satisfaction

Quality of life and satisfaction will be evaluate by questionnaire as Questionnaire SLEQOL, QUESTIONNAIRE LUPUSQOL, QUESTIONNAIRE MFI-20

Time frame: participants will be followed for the duration of hospital stay, an expected average of 3 months

Secondary Outcomes

Clinical data

Question about any recent hospitalization pregnancy contraception Compliance score of Girerd Fatigue score MFI-20 tobacco consumption Score of CES-D depression Score stress response WCC