Correlation Between Aqueous Protein Level and Clinical Grading of Flare and Flaremetry.

N/ACompletedNCT01905579

The Eye Center and The Eye Foundation for Research in Ophthalmology20 enrolled

Overview

The purpose of this study is to compare flaremetry readings with the protein content of the aqueous humor and the clinical grading of flare.

A total of 20 patients will be included. 10 patients with uveitis and 10 control patients scheduled for phacoemulsification. Each patient will undego complete ophthalmic examination and clinical biomicroscopic grading of the anterior chamber flare applying the SUN working group grading system. Aqueous specimens will be obtained by anterior chamber paracentesis for protein analysis. Each Patient will undego paracentesis and 0.2 ml of aqueous will be obtained. The aqueous sample will be stored at -70°C until the time of analysis for protein content. Objective assessment of flare will be done.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Uveitis

Interventions

Paracentesis of the anterior chamberPROCEDURE

Aqueous humor parenthesis for quantitative protein analysis in patients with and without uveitis.

Eligibility

Sex: ALLMin age: 10 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 10 patients with uveitis with cataract * 10 patients without uveitis with cataract * Inactive inflammation for at least 3 months Exclusion Criteria: * Infectious uveitis * endophthalmitis * cases with corneal scar

Locations (1)

The Eye Center

Riyadh, Saudi Arabia

Outcomes

Primary Outcomes

compare flaremetry readings with the protein content of the aqueous humor

Compare flaremetry readings with the protein content of the aqueous and the clinical grading.

Time frame: one month

Data from ClinicalTrials.gov

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