An Open Label Study Assessing the 24-hour Intraocular Pressure Pattern in PAC and PACG Patients, Before and After Laser Peripheral Iridotomy

Inclusion Criteria: * Diagnosis of primary angle closure (PAC) or primary angle closure glaucoma (PACG) with indication for laser peripheral iridotomy (PAC is defined by the presence of a partial or complete iridotrabecular contact in more than 2 quadrants with either raised intraocular pressure \[i.e. more than 21 mmHg\] and/or primary adhesion to the trabecular meshwork (peripheral anterior synechiae \[PAS\]; however, with normal optic disc and visual field. PACG is defined by the presence of iridotrabecular contact with either raised intraocular pressure and/or PAS, and evidence of glaucomatous optic disc and visual field) * No intraocular pressure-lowering drug treatment or a 4-week wash-out period prior to study day 0 and throughout the study * Aged ≥18 years, of either sex * Not more than 6 diopters spherical equivalent on the study eye * Not more than 2 diopters cylinder equivalent on the study eye * Have given written informed consent, prior to any investigational procedure Exclusion Criteria: * History of acute angle closure glaucoma * Secondary angle closure glaucoma * History of ocular surgery within the last 3 months * History of ocular laser treatment, including previous laser peripheral iridotomy * Corneal or conjunctival abnormality precluding contact lens adaptation * Severe dry eye syndrome * Patients with allergy to corneal anesthetic * Patients with contraindications for silicone contact lens wear * Patients not able to understand the character and individual consequences of the investigation * Participation in other clinical research within the last 4 weeks