Psychotic symptoms (hallucinations and delusions) are present in several psychiatric and neurological disorders as well as in the general population. Effective treatment strategies for these symptoms in all patients are lacking and treatment-response can presently not be predicted. To date, the exact pathophysiological mechanism of these symptoms remains unknown. By investigating (subtypes) of hallucinations and delusions in all populations, a common pathway may be found, leading to more effective treatment options. Alternatively, different subtypes may be associated with different pathophysiological mechanisms.
Study Type
OBSERVATIONAL
Enrollment
700
VU Medical Center
Amsterdam, Netherlands
RECRUITINGUMC Groningen
Groningen, Netherlands
NOT_YET_RECRUITINGParnassia Bavo Groep
The Hague, Netherlands
RECRUITINGThe number of clusters of patients with shared symptom profiles as determined by latent class analysis, and the difference in scores on cognitive assessment between these identified clusters.
Time frame: Three years
The internal consistency, test-retest reliability, inter-rater reliability, criterion validity and construct validity of a newly developed questionnaire.
Time frame: Two years
The difference in scores on cognitive assessment between participant groups with and without psychotic symptoms.
Time frame: Three years
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UMC Utrecht
Utrecht, Netherlands