Strenuous exercise or exercise involving eccentric muscle contractions can lead to muscle damage and changes in muscle function; this is known as exercise-induced muscle damage (EIMD). It is known that brief, repeated periods of ischemia followed by reperfusion, known as Ischemic Preconditioning (IPC) cause a delay in cell injury in cardiac muscle as well as in various other organs. Therefore the purpose of this study is to: 1. Quantify the use of IPC in recovery following EIMD. 2. Identify any effect of IPC during recovery on muscle function
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
24
St Marys Umiversity College
London, United Kingdom
Change from baseline in maximal voluntary contraction
Isometric MVC of the participants' dominant knee extensors was assessed using a strain gauge. MVCs were performed for 3 s with a 60 s rest between each repetition. The change in MVC will be determined 24, 48 and 72 hours following pre exercise conditions.
Time frame: pre exercise, 24 hours post, 48 hours post and 72 hours post exercise
Change from baseline in Creatine kinase
Plasma CK was determined from an earlobe capillary blood sample. The sample (10 microlitres) was analysed immediately using an semi-automated clinical chemistry analyser. The change in CK will be determined 24, 48 and 72 hours following pre exercise conditions
Time frame: pre exercise, 24 hours post, 48 hours post and 72 hours post exercise
Change from baseline in Limb girth
Mid-thigh and calf circumference was assessed as a measure of limb swelling using an anthropometric tape measure. Both measures were obtained with the participant in a standing position. The change in limb girth will be determined 24, 48 and 72 hours following pre exercise conditions
Time frame: pre exercise, 24 hours post, 48 hours post and 72 hours post exercise
Chnage from baseline in Vertical jump
Vertical jump (VJ) performance was assessed using an electronic timing mat with hands placed on hips and participants dropping down to a self-selected level before jumping maximally. The change in VJ will be determined 24, 48 and 72 hours following pre exercise conditions
Time frame: pre exercise, 24 hours post, 48 hours post and 72 hours post exercise
Change from baseline in Muscle soreness
Muscle soreness - Participants were asked to perform and hold a squat (90° knee angle) whilst they rated their perceived muscle soreness on a 200 mm visual analogue scale. The scale consisted of a line from 0 mm (no pain) to 200 mm (unbearably painful). The change in muscle soreness will be determined 24, 48 and 72 hours following pre exercise conditions
Time frame: pre exercise, 24 hours post, 48 hours post and 72 hours post exercise
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