Effects of Systemic Lidocaine on Postoperative Quality of Recovery After Robot-assisted Thyroidectomy

N/ACompletedNCT01907997

Yonsei University90 enrolled

Overview

Systemic lidocaine infusion may improve the patients' recovery quality and chronic post surgical pain after robot-assisted thyroidectomy

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Thyroid Cancer

Interventions

Systemic intravenous lidocaine infusionDRUG

In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.

normal saline infusionDRUG

In group C, the patients receive same volume of normal saline

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 20-65 * ASA class I and II * Thyroid cancer patients who are scheduled for elective robot-assisted thyroidectomy Exclusion Criteria: * Allergy to local anesthetics or contraindication to use of lidocaine * Pregnancy * Severe cardiovascular disease * Renal failure * Liver failure * Neurologic and psychologic disease * Chronic treatment with analgesics

Locations (1)

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei universiy college of medicine

Seoul, South Korea

Outcomes

Primary Outcomes

Quality of recovery 40(QoR-40) score

Assessing change of the Quality of recovery 40(QoR-40) score between 24hours before and after operation

Time frame: 24hours after operation day

Secondary Outcomes

Assessing the presence of chronic postsurgical pain(CPSP)

Time frame: 24hours after operation day

aspect and site of CPSP

Time frame: 24hours after operation day

Data from ClinicalTrials.gov

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