To investigate and compare the effects of Traumeel®S tablets versus placebo on exercise induced muscle damage and muscle soreness for 72 hours after strenuous eccentric exercise test on downhill treadmill.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
96
oral, Day 1: one tablet every 15 minutes for two hours after the exercise test, 6 hours and 10 hours after the exercise test; Day 2 and 3: two tablets thrice daily; Day 4: two tablets in the morning
oral, Day 1: one tablet every 15 minutes for two hours after the exercise test, 6 hours and 10 hours after the exercise test; Day 2 and 3: two tablets thrice daily; Day 4: two tablets in the morning
Department of Sports Medicine, Institute of Sports Science, University of Giessen
Giessen, Germany
Changes in post-exercise two baseline levels up to 72-hours of primary muscle damage marker creatine kinase (CK)
Time frame: 72 hours
Changes in post-exercise two baseline levels up to 72-hours Short Form McGill Questionnaire total scores and separate VAS pain ratings
Time frame: 72 hours
Changes in post-exercise two baseline levels up to 72-hours of immunomodulators (35 lab parameters)
Time frame: 72 hours
Changes in post-exercise two baseline levels up to 72-hours of immune status and activation markers (7 lab parameters)
Time frame: 72 hours
Changes in post-exercise two baseline levels up to 72-hours of maximum isometric strength (thigh flexors and extensors)
Time frame: 72 hours
Changes in post-exercise two baseline levels up to 72-hours of muscle marker Lactate Dehydrogenase
Time frame: 72 hours
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