The study will be conducted to evaluate the efficacy and safety of a topical dimeticone formulation (Loion®) compared to 10% salicylic acid in octyl-dodecanol with 15% Macrogol-4-laurylether for the removal of scaling in patients with chronic psoriasis capitis (scalp psoriasis).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
90
The treatment will be carried out once daily (in the evening) onto all scaling areas of the scalp over a period of 2 weeks, with the last application of investigational products being applied one day prior to the final visit.
The treatment will be carried out once daily (in the evening) onto all scaling areas of the scalp over a period of 2 weeks, with the last application of investigational products being applied one day prior to the final visit.
University Medical Center Hamburg-Eppendorf (UKE)
Hamburg, Germany
Change from Baseline in Scaling
To evaluate improvement of scaling of patients exposed to Loion or standard therapy for psoriasis capitis
Time frame: at Day 7
Psoriasis Scalp Severity Index (PSSI)
To evaluate clinical outcome of patients exposed to Loion or standard therapy for psoriasis capitis
Time frame: at Day 0, day 3, day 7, day 14
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