Protect - The Impact of a High Protein Diet on Preservation of Muscle Mass

N/ACompletedNCT01915030

Wageningen University61 enrolled

Overview

The present study is designed to investigate whether a high protein diet will preserve muscle mass during caloric restriction in older adults.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Obesity

Interventions

High protein dietOTHER

controlled feeding trail. Both arms are caloric restricted

standard protein dietOTHER

Eligibility

Sex: ALLMin age: 55 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Overweight and obese subjects (BMI 27-40 kg/m2) * Waist circumference male:≥ 102 cm, female: ≥ 88 cm * Willingness and ability to comply with the protocol Exclusion Criteria: * Renal insufficiency * Co-morbidities * Type 1 \& 2 diabetics (Fasting glucose level ≥ 7 mmol/L) * Cancer * COPD * Participation in weight loss program 3 months before the intervention * Participation of any heavy resistance-type exercise training (\>1 wk) the last 2 y. * Intentional or unintentional weight loss (\> 3 kg in the last 3 months) * Severe loss appetite * Diagnosed allergy to milk products * Gastric bypass * Supplements or medication use for weight loss * Participation in any other intervention trial * Women can only participate if they are postmenopausal (last period ≥ a year ago)

Locations (1)

Wageningen University

Wageningen, Gelderland, Netherlands