Safety and Efficacy of Dinoprostone (Propess) in the Women With Premature Rupture of Membrane or Gestational Age <38

Phase 2CompletedNCT01916291

Seoul National University Hospital189 enrolled

Overview

Dinoprostone(propess) is commonly used for induction of labor in the pregnant women who has intact membrane after 38weeks of gestational age. The investigators study safety and efficacy of dinoprostone in the pregnant women with premature rupture of membrane or GA\<38weeks

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

189

Conditions

Induction of Labor

Interventions

Propess insertion groupDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant women who admitted for induction of labor * Bishop score \<= 6 Exclusion Criteria: * Contraindication to induction of labor * Active labor * Vaginal bleeding, unknown origin * Hypersensitive to Prostaglandin E * History of asthma, glaucoma * Infection (birth canal) * Placental abruption * Multiparity(\>5) * Pelvic inflammatory disease * Heart, lung, kidney disease * Multiple pregnancy * Major anomaly * Fetal distress before induction of labor

Locations (2)

Seoul National University Hospital

Seoul, South Korea

Seoul Metropolitan Goverment Seoul National University Boramae Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Induction success rate after propess insertion

Time frame: Day 1 after propess insertion

Secondary Outcomes

Concentration of prostaglandinE

Time frame: at delivery

Data from ClinicalTrials.gov

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