Intralipid Therapy for Women 35-40 Years With Positive Natural Killer Cells Undergoing Intracytoplasmic Sperm Injection (ICSI)

Inclusion Criteria: Subfertile women aged 35-40 years with repeated implantation failure or recurrent miscarriage with positive natural killer cells undergoing Intracytoplasmic sperm injection (ICSI ) cycle. Exclusion Criteria: * women above 40years or less than 35 years * Disturbances of normal fat metabolism such as pathologic hyperlipidemia,Lipoid nephrosis or acute pancreatitis with hyperlipidemia. * Allergic to eggs, soybean oil, or safflower oil. * Severe liver disease, kidney disease, lung disease, anemia, blood coagulation disorder. * Uterine fibroid, endometrial polyp, endometriosis and hydrosalpinx. * Antiphospholipid syndrome (lupus anticoagulant and/or anticardiolipin antibodies (Immunoglobulin G or M)\[IgG or IgM\]); other recognised thrombophilic conditions (testing according to usual clinic practice). * Intrauterine abnormalities (as assessed by ultrasound, hysterosonography, hysterosalpingogram, or hysteroscopy). * Fibroids distorting uterine cavity. * Abnormal parental karyotype.